Evidence item

GEN reports prime assembly demonstrations of exon recoding, transgene integration, and megabase-scale rearrangements in primary human cells. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 23709

Source: Prime Assembly Expands Genome Editing with Precise, Large-Scale DNA Integration · locator {} · excerpt hash sha256:03f2f8f9bc523c063b446fbc2a04aea13f7bfb0b152d713b5377bfeca7b91340

The team applied prime assembly to perform targeted exon recoding, transgene integration, and megabase-scale rearrangements, including at therapeutically relevant loci in primary human cells.