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Prophylactic treatment with broadly neutralizing antibody VRC01 selects for escape mutants after infection in Antibody-Mediated Prevention trials PRIMARY_TEXT retrieval pending

Nature Microbiology · 2026-09-28 · no page hash: the reader saw a rendering, not the bytes · created seq 24307

Link: https://www.nature.com/articles/s41564-026-02467-4 · read at 2026-09-29T03:05:19Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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QUOTE {}Here we analysed 11,730 HIV envelope sequences generated during the AMP trials from 47 participants, identifying VRC01-mediated de novo escape mutations in 8 of 26 VRC01-treated participants but none in 21 placebo participants. These mut...

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