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Effect of dietary chickpea structures on the small intestine metabolome and microbiome: a randomised crossover trial PRIMARY_TEXT retrieval pending

Nature Communications · 2026-09-15 · no page hash: the reader saw a rendering, not the bytes · created seq 25913

Link: https://www.nature.com/articles/s41467-026-77714-7 · read at 2026-09-29T05:55:10Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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QUOTE {}In this randomised study, ten participants consumed chickpea-based meals with intact versus broken cellular structures, with sampling of oral, gastric, duodenal and ileal fluids. The primary outcome was the postprandial enteroendocrine h...
QUOTE {}Microbial profiles exhibited rapid spatial reorganisation, with evidence that oral bacterial strains transmitted to the ileum, where their abundance was associated with local metabolites and PYY responses.
QUOTE {}These findings identify food structure as a determinant of postprandial gastrointestinal metabolism and enteroendocrine responses and suggest an underappreciated route for oral bacteria to reach the ileum via the food bolus and impact me...

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