Claim
In the study’s Indian hospital-based analysis, three ROTASIIL doses had estimated adjusted effectiveness of 88% against rotavirus-gastroenteritis hospitalization among children aged 3–5 months.
Topics
Vaccines · 1efd24fe Public health · 1efd24fe
Assessment
Supported
Main unresolved issue: 4 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:0a075e33-7e45-85ac-87b0-2f6f8a050ce7
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.
Why?
Strongest counted support: The primary study reports the age-specific adjusted effectiveness estimate for children aged 3–5 months. weight 2.000000 evidence
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.
0.8808 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 4 sources, 1 independent lineage
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| 14f97a38 qualify | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (non directional) |
| 9e7261c7 support | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 2.000000 |
| be942af4 qualify | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (non directional) |
| 531a3247 qualify | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (non directional) |
prior 0.50 → log-odds 0.000000 + 2.000000 (the counted weights) = 2.000000 → probability 0.8808
Your view
Registered views
Nobody has registered a view yet.
Checked as part of
- “A 2026 Nature Communications test-negative case-control analysis in India estimated adjusted effectiveness of the three-dose ROTASIIL rotavirus vaccine...” · 3 claims · 29 September 2026
Evidence for
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Primary vaccine-effectiveness estimate.
Evidence against
None.
Qualifications
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Dose count, effectiveness estimate, outcome, and age group are explicit; study-setting qualifier is absent.
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Suppressed as dependent
None.
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 14f97a38, 9e7261c7, be942af4, 531a3247 |
Summary
Supported. The main support is: The primary study reports the age-specific adjusted effectiveness estimate for children aged 3–5 months. 301348c8
Qualifier: The 88% figure is the highest age-specific adjusted effectiveness estimate, with a 53–97 confidence interval, among completed three-dose cases aged 3–5 months. c266de26
Qualifier: The estimate comes from pooled observational test-negative case-control studies at 32 hospitals in seven Indian states during July 2019–December 2023. 32a8a794
Qualifier: The passage reports 88% adjusted effectiveness after three doses among 3–5-month-olds, but does not state the Indian hospital-based analysis. c0df096e
Review checks: 1 of 4. coverage:0a075e33-7e45-85ac-87b0-2f6f8a050ce7
Contribution history
| seq | event | detail |
|---|---|---|
| 19426 | APPENDED | |
| 19427 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 19444 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 24776 | TASK_RESULT | by 1efd24fe (accepted) |
| 25977 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
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