As of snapshot 27745 under ledger-default@0.3.0. Counts by assessment state, descriptive only: no topic is scored.
1 Contradicted1 Insufficient evidence1 Leans supported1 Not assessed35 Supported
| Claim | Type | Assessment |
|---|
| Over a median 3.32-year follow-up, intensive systolic blood-pressure lowering was associated with lower primary cardiovascular-outcome risk than standard treatment across metabolic-syndrome tertiles; the largest reduction was in the middle tertile (HR 0.66, 95% CI 0.44–0.99). | QUANTITATIVE | Supported |
| Among 205 adolescents at high risk for gaming disorder or unspecified internet use disorder, PROTECTtraining had lower 12-month symptom severity than PROTECTinfo, with between-group Cohen’s d −0.30 (95% CI −0.55 to −0.05). | QUANTITATIVE | Supported |
| At post-intervention, One Step Back participants reported lower depression scores by 5.54 points and higher well-being by 4.53 points than active controls. | QUANTITATIVE | Supported |
| In the study, observed outbreak reporting declined by a median of 32% for each additional hour of travel time from a health facility. | QUANTITATIVE | Supported |
| The study found outbreak risks were typically highest in mosaic landscapes where people and livestock coexist alongside forests and fragmented ecosystems, especially for several vector-borne diseases. | OBSERVATIONAL | Supported |
| The study consolidated 58,319 outbreak-event records covering 32 emerging infectious diseases to test social and environmental drivers of outbreak geography. | QUANTITATIVE | Supported |
| The study's analysis of APN orthologues from 93 species found restricted EriCoV receptor tropism, primarily using hedgehog APN and, to a lesser extent, felid APN. | QUANTITATIVE | Supported |
| In a global analysis of 58,319 outbreak event records for 32 diseases, reporting declined by a median of 32% for each additional hour of travel time from a health facility. | QUANTITATIVE | Insufficient evidence |
| In a seven-year biomonitoring study of 1,003 Barred Owls in northwestern California, second-generation anticoagulant exposure among young owls fell from about 50% in 2019 to about 20% in 2024, while vitamin D3 rodenticide was detected in 18.5% overall and all rodenticides in up to 46%. | QUANTITATIVE | Supported |
| In a 15-cluster Singapore randomized trial, releases of irradiated Wolbachia wAlbB-infected male Aedes aegypti were associated with time-varying reductions in dengue incidence and an estimated 2,351 cases averted, though the effect attenuated during an inter-epidemic period. | QUANTITATIVE | Leans supported |
| The study analyzed 2,243 children aged 3–23 months hospitalized with acute gastroenteritis, of whom 638 were ELISA-positive for rotavirus. | QUANTITATIVE | Supported |
| In the study’s Indian hospital-based analysis, three ROTASIIL doses had estimated adjusted effectiveness of 56% against moderate rotavirus gastroenteritis and 54% against severe rotavirus gastroenteritis among children aged 3–23 months. | QUANTITATIVE | Supported |
| In the study’s Indian hospital-based analysis, three ROTASIIL doses had estimated adjusted effectiveness of 88% against rotavirus-gastroenteritis hospitalization among children aged 3–5 months. | QUANTITATIVE | Supported |
| In the NOHARM stepped-wedge cluster-randomized trial across six surgical centers, an EHR-based strategy promoting nondrug pain management reduced postoperative opioid exposure without worsening patient-reported pain interference, physical function, or reported safety outcomes. | QUANTITATIVE | Supported |
| Across 357 Minnesota lakes, zebra mussel establishment was associated with increased mercury in harvestable-sized fish of four of six species, with species-specific increases of 6% to 21% and higher threshold exceedance risk in some fish. | QUANTITATIVE | Supported |
| In the 2026 HERBOT phase 1b/2 study of 40 participants with previously untreated HER2-positive advanced biliary tract cancer, median progression-free survival was 10.6 months with the trastuzumab-nivolumab-gemcitabine-cisplatin regimen. | QUANTITATIVE | Supported |
| In the 2026 HERBOT phase 1b/2 study of 40 participants with previously untreated HER2-positive advanced biliary tract cancer, the trastuzumab-nivolumab-gemcitabine-cisplatin regimen had a 95% disease-control rate. | QUANTITATIVE | Supported |
| A 2026 systematic review and meta-analysis reported that laboratory-confirmed enteric infection was associated with higher odds of childhood stunting, while grading the certainty of the evidence as very low. | QUANTITATIVE | Supported |
| In a murine MRSA infection model, IMP-2380 combined with ciprofloxacin produced a significant 100-fold reduction in bacterial burden, with three of five infections below the assay detection limit. | QUANTITATIVE | Supported |
| In an Ethiopian phase II randomized trial of 183 adults with localized Leishmania aethiopica cutaneous leishmaniasis, single-session thermotherapy and weekly intralesional sodium stibogluconate had comparable intention-to-treat cure rates, while per-protocol final cure favored drug treatment; no serious adverse events occurred. | QUANTITATIVE | Supported |
| In a cluster-randomized trial of 400 permanent-supportive-housing residents, a brief smoke-free-home intervention did not significantly increase adoption maintained for at least 90 days at six months, although it increased one-day smoke-free-home adoption and seven-day point-prevalence abstinence. | QUANTITATIVE | Supported |
| In the Southwest Ethiopia study, presumptive E. coli, Salmonella spp., Shigella spp., and Listeria spp. were observed at 42.1%, 29.2%, 18.6%, and 13.5%, respectively, across water, beef, and environmental samples, with significant variation by sample type and source. | QUANTITATIVE | Supported |
| A Southwest Ethiopia slaughter-to-plate study collected 349 samples from water, beef cuts, colon contents, and carcass swabs across a catchment river, two abattoirs, and 44 randomly selected beef retailers between February and May 2024. | QUANTITATIVE | Supported |
| In the NHS-Galleri trial's evaluable intervention participants across three annual rounds, the multi-cancer early-detection test had 99.50–99.60% specificity and 26.7–37.2% episode sensitivity for all cancers; these performance analyses were descriptive and the trial's primary late-stage-cancer endpoint was not met. | QUANTITATIVE | Supported |
| In the PATHFINDER 2 study, among 32,007 performance-analyzable participants, the multi-cancer early-detection test had a 0.54% cancer detection rate, 60.3% positive predictive value, 99.2% negative predictive value, and 99.64% specificity. | QUANTITATIVE | Supported |
| In this real-world case-control study, prior metformin use was not associated with a statistically distinguishable difference in SARS-CoV-2 susceptibility (aOR 0.97, 95% CI 0.81–1.16). | QUANTITATIVE | Supported |
| In this real-world case-control study, prior metformin use was associated with lower odds of COVID-19 hospitalization and disease progression than use of no antidiabetic medication (hospitalization aOR 0.70, 95% CI 0.51–0.97; progression aOR 0.66, 95% CI 0.45–0.98). | QUANTITATIVE | Supported |
| In the reported study, the wearable optoacoustic device agreed with a reference cuff-based blood-pressure monitor, supporting its potential for continuous cuffless monitoring. | COMPARATIVE | Supported |
| In the reported study, the silicon-photonics optoacoustic detector measured high-contrast radial-artery signals at 100 Hz and captured features of the blood-pressure waveform. | OBSERVATIONAL | Supported |
| The study reported that the CMIP6 inventory overestimated black-carbon radiative forcing by 45%. | QUANTITATIVE | Supported |
| A study using a localized black-carbon inventory and revised health-risk function estimated that over 540,000 premature deaths were attributable to black carbon in China in 2015. | QUANTITATIVE | Supported |
| In the same phase 1b/2 study, the regimen produced a 95% disease-control rate among the 40 analyzed participants. | QUANTITATIVE | Supported |
| In a South Korean phase 1b/2 study of 40 participants with previously untreated HER2-positive advanced biliary tract cancer, the trastuzumab-nivolumab-gemcitabine-cisplatin regimen produced a 55% objective response rate. | QUANTITATIVE | Supported |
| WHO reported that more than 40% of planned insecticide-treated-net campaigns designed to reach 425 million people were delayed or at risk of derailment by early April 2025. | QUANTITATIVE | Supported |
| WHO reported that more than half of 64 surveyed malaria-endemic countries experienced moderate or severe disruptions to malaria services after funding cuts. | QUANTITATIVE | Supported |
| More than 150,000 people die on Earth each day. | QUANTITATIVE | Supported |
| Longevity should be treated as economic policy rather than a luxury, because a healthy 80-year-old is an economic contributor rather than a pension liability. | NORMATIVE | Not assessed |
| The global population over 65 is projected to grow from 852 million in 2025 to 2 billion by 2060, accounting for more than half of all population growth in that period. | QUANTITATIVE | Contradicted |
| Conservative estimates hold that 45 per cent of dementia cases are entirely preventable. | QUANTITATIVE | Supported |
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