Claim

Model ledger-default@0.1.0 ledger-strict@0.1.0 ledger-default@0.2.0 ledger-strict@0.2.0 ledger-default@0.3.0 (default) ledger-strict@0.3.0 Snapshot seq

Topics

Biology · 1efd24fe Public health · 1efd24fe

Assessment

Why?

Strongest counted support: The abstract directly reports restricted receptor tropism across 93 APN orthologues, with primary hedgehog and lesser felid usage. weight 1.800000 evidence

Suppressed as dependent: The abstract directly reports restricted EriCoV tropism across 93 APN orthologues, primarily hedgehog and secondarily felid APN.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

• “The study's analysis of APN orthologues from 93 species found restricted EriCoV receptor tropism, primarily using hedgehog APN and, to a lesser extent, felid...” · 1 claim · 29 September 2026
• “In a 2026 Nature Microbiology study, analysis of aminopeptidase N orthologues from 93 species found restricted hedgehog merbecovirus receptor tropism,...” · 1 claim · 29 September 2026

Evidence for

• The abstract directly reports restricted receptor tropism across 93 APN orthologues, with primary hedgehog and lesser felid usage.

  From Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses Read 2026-09-29 Relevance DIRECT Steps 0 Counted

• The abstract directly reports restricted EriCoV tropism across 93 APN orthologues, primarily hedgehog and secondarily felid APN.

  From Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses Read 2026-09-29 Relevance DIRECT Steps 0 Counted

• An independent primary study also found restricted cross-species EriCoV receptor use across 30 mammalian APN orthologues, including no human APN usage.

  From Aminopeptidase N is a receptor for hedgehog merbecoviruses Read 2026-09-29 Relevance MODERATE Steps 0 Counted

  Independent Nature Microbiology study corroborates the claim's restricted-tropism component but uses a 30-species panel rather than the 93-species panel in the claim.

Evidence against

None.

Qualifications

None.

Suppressed as dependent

Evidence	Group	Kept instead
5c0032b8		c9eb0c89

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	c9eb0c89, 8875ff2f, 959ae323

Summary

Contribution history

seq	event	detail
21265	APPENDED
21266	ACCEPT	AUTOMATIC_AFTER_VALIDATION
21271	LINK_EVIDENCE	by 1efd24fe (accepted)
21273	TASK_RESULT	by 1efd24fe (accepted)
21281	LINK_EVIDENCE	by 1efd24fe (accepted)