Galedra
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Claim

In a triple-blind multicenter randomized trial of 132 patients with persistent schizophrenia symptoms, low-intensity transcranial random-noise stimulation produced no significant improvement over sham at day 5 or on secondary outcomes, though it was well tolerated.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 17950

35 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositions

Referenced 95 times: checked 1, looked up by assistants 0, viewed 72, shared 22. A count of attention, not evidence.

Topics

Medicine · 1efd24fe Health · 1efd24fe

Assessment

Supported

Score: 0.8581 under ledger-default@0.3.0 at snapshot 27745

2 of 4 review checks done · 1 counted · 1 by the author only

1 independent evidence lineage · review checks 1 of 4 · stability MEDIUM

Main unresolved issue: 3 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:23fd7841-9c0f-82d0-85a1-d192a31d5a31

Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from link.springer.com was not found on the page when Galedra fetched it.

Why?

Strongest counted support: The trial found no significant active-versus-sham difference at day five or in secondary outcomes and reported good tolerability. weight 1.800000 evidence

Suppressed as dependent: The packet directly supports the randomized sample, null day-five and secondary outcomes, and good tolerability.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

Hide calculation

0.8581 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 3 sources, 1 independent lineage

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:f9eccef7361ce44077daef877e7287b4a22de7da65169315b178211807492391

Last changed at entry seq 25374; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

LinkWorkingWeightCounted as
cef71919 qualify relevance MODERATE 0.6 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 0.540000 0.000000 (non directional)
72fb4b00 support relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 1.800000
884b1f02 support relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 0.000000 (dependent strongest only, kept 72fb4b00)

prior 0.50 → log-odds 0.000000 + 1.800000 (the counted weights) = 1.800000 → probability 0.8581

Under neighbouring settings of the same model: 0.7790 to 0.9121, a spread of 0.1331.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Sign in to register whether you agree or disagree. A view is yours alone and never changes the assessment.

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

Suppressed as dependent

EvidenceGroupKept instead
e1ca5cc472fb4b00

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedyescef71919, 72fb4b00, 884b1f02

Summary

Supported. The main support is: The trial found no significant active-versus-sham difference at day five or in secondary outcomes and reported good tolerability. ee0c9dd5

1 further item repeats the same origin and is not independent evidence. e1ca5cc4

Qualifier: The counted passage reports 64 and 68 patients by arm and the clinical outcomes, but omits the total 132-patient denominator and triple-blind multicenter design. c207df55

Review checks: 1 of 4. coverage:23fd7841-9c0f-82d0-85a1-d192a31d5a31

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
17950APPENDED
17951ACCEPTAUTOMATIC_AFTER_VALIDATION
17956LINK_EVIDENCEby 1efd24fe (accepted)
17985TASK_RESULTby 1efd24fe (accepted)
25373TASK_RESULTby 1efd24fe (accepted)

Score trace

{
  "claim": "23fd7841-9c0f-82d0-85a1-d192a31d5a31",
  "links": [
    {
      "link": "5a136b29-d965-8a43-9925-ede3cef71919",
      "group": null,
      "reason": "non_directional",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "aa2a3d43-cc49-82ef-82c9-bd6cc207df55",
      "direction": "QUALIFY",
      "magnitude": "0.540000",
      "relevance": "MODERATE",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "7712c1c1-6193-8c3a-80db-0cc872fb4b00",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "9f860b55-19b0-87c1-9920-1eb7ee0c9dd5",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DATASET_RESULT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "7712c1c1-6193-8c3a-80db-0cc872fb4b00",
      "link": "89b4ffac-7c64-84a1-8650-6da2884b1f02",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "14d052e8-026c-8424-83b3-bd8fe1ca5cc4",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DATASET_RESULT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1331",
    "permissive": "0.9121",
    "conservative": "0.7790"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8581",
  "provisional": true,
  "evidence_sum": "1.800000",
  "snapshot_seq": 25374,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [
        "5a136b29-d965-8a43-9925-ede3cef71919",
        "7712c1c1-6193-8c3a-80db-0cc872fb4b00",
        "89b4ffac-7c64-84a1-8650-6da2884b1f02"
      ],
      "ok": true
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "1.800000",
  "not_applicable_reason": null,
  "independence_unreviewed": 3
}