Claim
In an open-label pilot of 30 adults with Crohn’s disease, a single colonoscopic fecal microbiota transplant was associated with mucosal adherent-invasive E. coli decolonization in all 8 evaluable baseline-positive patients, with no FMT-related serious adverse events.
36 words; atomic claims are usually under 25a comma-separated series may list several propositionsTopics
Medicine · 1efd24fe Health · 1efd24fe
Assessment
Supported
Main unresolved issue: 4 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:4fd75235-d8aa-8171-bdde-18411fd5a207
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from emjreviews.com and nature.com was not found on the page when Galedra fetched it.
Why?
Strongest counted support: The pilot reported decolonization in all eight evaluable baseline-positive patients and no FMT-related serious adverse events. weight 1.800000 evidence
Suppressed as dependent: The packet directly supports the 30-person pilot, all-eight decolonization result, and absence of serious FMT-related adverse events.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.
0.9468 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability HIGH · 4 sources, 2 independent lineages
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| 1f146007 qualify | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 0.000000 (non directional) |
| 53d7baa4 support | relevance STRONG 1.2 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.080000 | 1.080000 |
| 6070466d support | relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 1.800000 |
| 92973c1a support | relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (dependent strongest only, kept 6070466d) |
prior 0.50 → log-odds 0.000000 + 2.880000 (the counted weights) = 2.880000 → probability 0.9468
Your view
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Checked as part of
- “In an open-label pilot of 30 adults with Crohn’s disease, a single colonoscopic fecal microbiota transplant was associated with mucosal adherent-invasive E....” · 1 claim · 29 September 2026
- “In an open-label pilot of 30 adults with Crohn’s disease, a single colonoscopic fecal microbiota transplant was associated with mucosal adherent-invasive E....” · 1 claim · 29 September 2026
Evidence for
-
From Fecal microbiota transplantation for the decolonization of mucosal adherent-invasive Escherichia coli in Crohn’s disease: an open-label pilot study Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From FMT Targets Mucosal E. coli in Crohn’s Disease Read 2026-09-29 Relevance STRONG Steps 0 Counted
Independent secondary coverage reports the principal pilot outcome and safety finding.
-
From Fecal microbiota transplantation for the decolonization of mucosal adherent-invasive Escherichia coli in Crohn’s disease: an open-label pilot study Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Evidence against
None.
Qualifications
-
From Fecal microbiota transplantation for the decolonization of mucosal adherent-invasive Escherichia coli in Crohn’s disease: an open-label pilot study Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Adds follow-up window, selection criterion, sample source, and pilot endpoint scope.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| e9285003 | 6070466d |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 1f146007, 6070466d, 92973c1a |
Summary
Supported. The main support is: Independent gastroenterology coverage corroborates decolonization in all eight evaluable baseline-positive patients and the absence of serious FMT-related adverse events. 80f532f9
1 further item repeats the same origin and is not independent evidence. e9285003
Qualifier: The decolonization result was a 12-week, mucosal-assay endpoint in eight evaluable baseline-positive adults selected for serum anti-E. coli antibody positivity. 4b870973
Review checks: 1 of 4. coverage:4fd75235-d8aa-8171-bdde-18411fd5a207
Contribution history
| seq | event | detail |
|---|---|---|
| 17719 | APPENDED | |
| 17720 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 17725 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 17733 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 17739 | TASK_RESULT | by 1efd24fe (accepted) |
| 25358 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
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