Claim
Cryo-electron microscopy reportedly resolved DILT fibrils at 2.9–4.0 Å, with a repeating unit of 12 peptide chains and C6 symmetry.
Topics
Assessment
Supported
Main unresolved issue: 3 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:84cd1e46-948d-8064-a2a8-fa9f4b481b79
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from tldrdailynews.com was not found on the page when Galedra fetched it.
Why?
Strongest counted support: The report gives 2.9–4.0 Å cryo-EM resolution and a 12-chain C6-symmetric repeating unit. weight 2.000000 evidence
Suppressed as dependent: The excerpt directly reports 2.9–4.0 Å cryo-EM resolution, a 12-chain repeating unit, and C6 symmetry for DILT fibrils.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.
Your view
Registered views
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Checked as part of
- “A 2026 report on a Nature study describes nine-residue DILT peptides that assemble into hexagonal nanofibrils with approximately 5-nm channels, and reports...” · 3 claims · 29 September 2026
Evidence for
-
From Nine-residue peptides encode hexagonal nanochannel lattices via specific interaction motifs Read 2026-09-29 Relevance DIRECT Steps 0 Counted
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From Nine-residue peptides encode hexagonal nanochannel lattices via specific interaction motifs Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Evidence against
None.
Qualifications
-
From Sequence-encoded hexagonal lattices in multichannel peptide nanofibrils Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Clarifies that resolution and symmetry refer to distinct DILT1 morphologies under the reported assembly conditions.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| cc00f954 | 7d9b7dec |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 99f45a8b |
Summary
Supported. The main support is: The report gives 2.9–4.0 Å cryo-EM resolution and a 12-chain C6-symmetric repeating unit. 1f6c20c2
1 further item repeats the same origin and is not independent evidence. cc00f954
Qualifier: The 2.9–4.0 Å range spans distinct DILT1 morphologies with 12% and 73% relative abundance; the 12-chain C6 unit is their specific reported architecture. 5e3d8bf6
A search for evidence in the opposing direction found none. 98f471da
Review checks: 1 of 4. coverage:84cd1e46-948d-8064-a2a8-fa9f4b481b79
Contribution history
| seq | event | detail |
|---|---|---|
| 23815 | APPENDED | |
| 23816 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 23831 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 24450 | TASK_RESULT | by 1efd24fe (accepted) |
| 25302 | TASK_RESULT | by 1efd24fe (accepted) |