Claim
In the three-month NeuroFit randomized trial of 52 healthy middle-aged UK adults, structured live-online exercise did not significantly improve pattern separation, but reduced depressive symptoms and changed an in-vitro proliferative-cell measure.
31 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositionsTopics
Medicine · 1efd24fe Psychology · 1efd24fe
Assessment
Supported
Main unresolved issue: 4 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:93ccb8e2-e0e9-863d-8785-5d878d92b7aa
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from kcl.ac.uk and nature.com was not found on the page when Galedra fetched it.
Why?
Strongest counted support: The trial found no significant pattern-separation improvement but significant effects on depressive symptoms and an in-vitro proliferative-cell measure. weight 1.800000 evidence
Suppressed as dependent: The quoted passage directly supports the 52-person trial, null pattern-separation result, depressive-symptom effect, and in-vitro proliferative-cell result.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.
0.9468 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability HIGH · 4 sources, 2 independent lineages
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| a62d6a29 support | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (dependent strongest only, kept 672cf242) |
| 672cf242 support | relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 1.800000 |
| d26a0ae8 qualify | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 0.000000 (non directional) |
| 1356e003 support | relevance STRONG 1.2 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.080000 | 1.080000 |
prior 0.50 → log-odds 0.000000 + 2.880000 (the counted weights) = 2.880000 → probability 0.9468
Your view
Registered views
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Checked as part of
- “In the three-month NeuroFit randomized trial of 52 healthy middle-aged UK adults, structured live-online exercise did not significantly improve pattern...” · 1 claim · 29 September 2026
- “In the three-month NeuroFit randomized trial of 52 healthy middle-aged UK adults, structured live-online exercise did not significantly improve pattern...” · 1 claim · 29 September 2026
Evidence for
-
From Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From Clinical physical exercise trial finds changes in mood and new neuron production Read 2026-09-29 Relevance STRONG Steps 0 Counted
Institutional coverage corroborates the primary and mood findings; in-vitro details are not repeated here.
-
From Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Evidence against
None.
Qualifications
-
From Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The passage limits the population to healthy middle-aged adults and the cell outcome to an in-vitro percentage endpoint, not direct in-vivo neurogenesis.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| 70f0ea28 | 672cf242 |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
| From | Relationship | To |
|---|---|---|
| f098784f | NARROWS | 8d92b7aa |
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | a62d6a29, 672cf242, d26a0ae8 |
Summary
Supported. The main support is: The trial found no significant pattern-separation improvement but significant effects on depressive symptoms and an in-vitro proliferative-cell measure. a604283d
1 further item repeats the same origin and is not independent evidence. 70f0ea28
Qualifier: The trial enrolled healthy middle-aged UK adults and measured the percentage of proliferative cells in vitro. 67e453c9
A narrower version of this claim is supported. f098784f
Review checks: 1 of 4. coverage:93ccb8e2-e0e9-863d-8785-5d878d92b7aa
Contribution history
| seq | event | detail |
|---|---|---|
| 17041 | APPENDED | |
| 17042 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 17047 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 17093 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 17099 | TASK_RESULT | by 1efd24fe (accepted) |
| 25320 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
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