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Claim

The DILT family of nine-residue amphiphilic peptides assembles into hexagonal nanofibrils with continuous approximately 5-nm solvent-accessible channels through cross-beta-dimer, trimeric-junction, and inversion motifs.

Type OBSERVATIONAL · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 23811 · qualifiers {"population":"DILT family of nine-residue amphiphilic peptides"}

a comma-separated series may list several propositions

Referenced 126 times: checked 1, looked up by assistants 0, viewed 89, shared 36. A count of attention, not evidence.

Topics

Chemistry · 1efd24fe Biology · 1efd24fe

Assessment

Supported

Score: 0.8581 under ledger-default@0.3.0 at snapshot 27745

2 of 4 review checks done · 0 counted · 2 by the author only

1 independent evidence lineage · review checks 0 of 4 · stability MEDIUM

Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:9641f884-13df-8d41-8a0e-6c1b5b0088c0

Not yet independently audited.Evidence reviewed so far supports this claim, but only 0 of 4 review checks have been done.Every quoted passage was confirmed on the page when Galedra fetched it.

Why?

Strongest counted support: The report describes nine-residue peptides assembling into honeycomb nanofibrils with approximately 5-nanometre solvent-accessible pores. weight 1.800000 evidence

Suppressed as dependent: The passage directly reports nine-residue peptides forming hexagonal nanofibrils with approximately 5-nanometre continuous solvent-accessible channels through the listed motifs.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed, primary source reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

Hide calculation

0.8581 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 0 of 4 · stability MEDIUM · 2 sources, 1 independent lineage

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:7188e9ed66f2ddf11d84869ffb734b9dba66b9933ea482e43642bac370aee663

Last changed at entry seq 25926; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

LinkWorkingWeightCounted as
0176766a support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 1.800000
cc04a650 support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 0.000000 (dependent strongest only, kept 0176766a)

prior 0.50 → log-odds 0.000000 + 1.800000 (the counted weights) = 1.800000 → probability 0.8581

Under neighbouring settings of the same model: 0.7790 to 0.9121, a spread of 0.1331.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Sign in to register whether you agree or disagree. A view is yours alone and never changes the assessment.

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

None.

Suppressed as dependent

EvidenceGroupKept instead
f41b4b730176766a

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 0 of 4

3 checks by this claim's own author. No independent review yet. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedno

Summary

Supported. The main support is: The report describes nine-residue peptides assembling into honeycomb nanofibrils with approximately 5-nanometre solvent-accessible pores. 35b036df

1 further item repeats the same origin and is not independent evidence. f41b4b73

A search for evidence in the opposing direction found none. 6fc67dc9

Review checks: 0 of 4. coverage:9641f884-13df-8d41-8a0e-6c1b5b0088c0

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
23811APPENDED
23812ACCEPTAUTOMATIC_AFTER_VALIDATION
23829LINK_EVIDENCEby 1efd24fe (accepted)
24240TASK_RESULTby 1efd24fe (accepted)

Score trace

{
  "claim": "9641f884-13df-8d41-8a0e-6c1b5b0088c0",
  "links": [
    {
      "link": "8f9822ed-d6ce-8122-97bc-85d20176766a",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "218ddc58-bec4-85c8-811f-2bcf35b036df",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "8f9822ed-d6ce-8122-97bc-85d20176766a",
      "link": "9f2ab100-f5d7-80b8-8ae0-ffe2cc04a650",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "0abe2d38-3c5b-8b88-9795-0880f41b4b73",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1331",
    "permissive": "0.9121",
    "conservative": "0.7790"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "OBSERVATIONAL",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8581",
  "provisional": true,
  "evidence_sum": "1.800000",
  "snapshot_seq": 25926,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.00",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [],
      "ok": false
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "1.800000",
  "not_applicable_reason": null,
  "independence_unreviewed": 2
}