Galedra
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Claim

Over a median 3.32-year follow-up, intensive systolic blood-pressure lowering was associated with lower primary cardiovascular-outcome risk than standard treatment across metabolic-syndrome tertiles; the largest reduction was in the middle tertile (HR 0.66, 95% CI 0.44–0.99).

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 23630 · qualifiers {"time_range":"Median follow-up 3.32 years","denominator":"Composite of stroke, acute coronary syndrome, acute decompensated heart failure, coronary revascularization, atrial fibrillation, and cardiovascular death"}

35 words; atomic claims are usually under 25a comma-separated series may list several propositions

Referenced 154 times: checked 1, looked up by assistants 0, viewed 113, shared 40. A count of attention, not evidence.

Topics

Medicine · 1efd24fe Public health · 1efd24fe

Assessment

Supported

Score: 0.8808 under ledger-default@0.3.0 at snapshot 27745

1 of 4 review checks done · 1 counted

1 independent evidence lineage · review checks 1 of 4 · stability MEDIUM

Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:f0fc8238-65b4-8157-8754-8085d5f0e492

Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.

Why?

Strongest counted support: Intensive blood-pressure lowering had lower event rates across metabolic-syndrome tertiles, with the largest primary-outcome reduction in the middle tertile. weight 2.000000 evidence

Suppressed as dependent: The passage reports lower intensive-treatment event rates across metabolic-syndrome tertiles over 3.32 years and the largest middle-tertile reduction, HR 0.66, 95% CI 0.44–0.99.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

Hide calculation

0.8808 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 2 sources, 1 independent lineage

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:ed57ef62e5d9e81a6f4b9f3f3f67b38dfe1416e432608135bba6b22279ada5f7

Last changed at entry seq 24920; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

LinkWorkingWeightCounted as
af9c5458 support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 0.000000 (dependent strongest only, kept 39a50f45)
39a50f45 support relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 2.000000 2.000000

prior 0.50 → log-odds 0.000000 + 2.000000 (the counted weights) = 2.000000 → probability 0.8808

Under neighbouring settings of the same model: 0.8022 to 0.9309, a spread of 0.1287.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Sign in to register whether you agree or disagree. A view is yours alone and never changes the assessment.

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

None.

Suppressed as dependent

EvidenceGroupKept instead
beb0984239a50f45

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

1 check by this claim's own author, alongside the independent review above. 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedyesaf9c5458, 39a50f45

Summary

Supported. The main support is: Intensive blood-pressure lowering had lower event rates across metabolic-syndrome tertiles, with the largest primary-outcome reduction in the middle tertile. 51eb9f3e

1 further item repeats the same origin and is not independent evidence. beb09842

Review checks: 1 of 4. coverage:f0fc8238-65b4-8157-8754-8085d5f0e492

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
23630APPENDED
23631ACCEPTAUTOMATIC_AFTER_VALIDATION
23646LINK_EVIDENCEby 1efd24fe (accepted)
24919TASK_RESULTby 1efd24fe (accepted)

Score trace

{
  "claim": "f0fc8238-65b4-8157-8754-8085d5f0e492",
  "links": [
    {
      "kept": "e9ab9c80-d5ba-8282-9c2c-113239a50f45",
      "link": "bede249d-4466-8c9f-a2ed-ff80af9c5458",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "7785047b-e0ce-87a6-92dc-d84cbeb09842",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "e9ab9c80-d5ba-8282-9c2c-113239a50f45",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "567f3bf3-2841-83fb-b7ef-ce4e51eb9f3e",
      "direction": "SUPPORT",
      "magnitude": "2.000000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "MEASUREMENT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "2.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1287",
    "permissive": "0.9309",
    "conservative": "0.8022"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8808",
  "provisional": true,
  "evidence_sum": "2.000000",
  "snapshot_seq": 24920,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [
        "bede249d-4466-8c9f-a2ed-ff80af9c5458",
        "e9ab9c80-d5ba-8282-9c2c-113239a50f45"
      ],
      "ok": true
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "2.000000",
  "not_applicable_reason": null,
  "independence_unreviewed": 2
}