Claim
Over a median 3.32-year follow-up, intensive systolic blood-pressure lowering was associated with lower primary cardiovascular-outcome risk than standard treatment across metabolic-syndrome tertiles; the largest reduction was in the middle tertile (HR 0.66, 95% CI 0.44–0.99).
35 words; atomic claims are usually under 25a comma-separated series may list several propositionsTopics
Medicine · 1efd24fe Public health · 1efd24fe
Assessment
Supported
Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:f0fc8238-65b4-8157-8754-8085d5f0e492
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.
Why?
Strongest counted support: Intensive blood-pressure lowering had lower event rates across metabolic-syndrome tertiles, with the largest primary-outcome reduction in the middle tertile. weight 2.000000 evidence
Suppressed as dependent: The passage reports lower intensive-treatment event rates across metabolic-syndrome tertiles over 3.32 years and the largest middle-tertile reduction, HR 0.66, 95% CI 0.44–0.99.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.
0.8808 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 2 sources, 1 independent lineage
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| af9c5458 support | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (dependent strongest only, kept 39a50f45) |
| 39a50f45 support | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 2.000000 |
prior 0.50 → log-odds 0.000000 + 2.000000 (the counted weights) = 2.000000 → probability 0.8808
Your view
Registered views
Nobody has registered a view yet.
Checked as part of
- “A 2026 post hoc analysis of the STEP randomized trial examined whether metabolic-syndrome severity modified intensive systolic blood-pressure lowering’s...” · 3 claims · 29 September 2026
Evidence for
-
From Metabolic syndrome severity and the effects of intensive blood pressure lowering: Results from the STEP randomized trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From Metabolic syndrome severity and the effects of intensive blood pressure lowering: Results from the STEP randomized trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Follow-up, cross-tertile direction, middle-tertile maximum, hazard ratio, and interval match.
Evidence against
None.
Qualifications
None.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| beb09842 | 39a50f45 |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | af9c5458, 39a50f45 |
Summary
Supported. The main support is: Intensive blood-pressure lowering had lower event rates across metabolic-syndrome tertiles, with the largest primary-outcome reduction in the middle tertile. 51eb9f3e
1 further item repeats the same origin and is not independent evidence. beb09842
Review checks: 1 of 4. coverage:f0fc8238-65b4-8157-8754-8085d5f0e492
Contribution history
| seq | event | detail |
|---|---|---|
| 23630 | APPENDED | |
| 23631 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 23646 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 24919 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
{
"claim": "f0fc8238-65b4-8157-8754-8085d5f0e492",
"links": [
{
"kept": "e9ab9c80-d5ba-8282-9c2c-113239a50f45",
"link": "bede249d-4466-8c9f-a2ed-ff80af9c5458",
"group": null,
"reason": "dependent_strongest_only",
"edition": "NAMED_OR_UNRELATED",
"evidence": "7785047b-e0ce-87a6-92dc-d84cbeb09842",
"direction": "SUPPORT",
"magnitude": "1.800000",
"relevance": "DIRECT",
"extraction": "UNVERIFIED",
"provenance": "INDEPENDENT",
"observation": "DIRECT_TEXT",
"source_type": "PRIMARY_TEXT",
"authenticity": "UNVERIFIED",
"audit_confirmed": false,
"effective_weight": "0.000000",
"interpretive_steps": 0
},
{
"link": "e9ab9c80-d5ba-8282-9c2c-113239a50f45",
"group": null,
"edition": "NAMED_OR_UNRELATED",
"evidence": "567f3bf3-2841-83fb-b7ef-ce4e51eb9f3e",
"direction": "SUPPORT",
"magnitude": "2.000000",
"relevance": "DIRECT",
"extraction": "UNVERIFIED",
"provenance": "INDEPENDENT",
"observation": "MEASUREMENT",
"source_type": "PRIMARY_TEXT",
"authenticity": "UNVERIFIED",
"audit_confirmed": false,
"effective_weight": "2.000000",
"interpretive_steps": 0
}
],
"model": "ledger-default@0.3.0",
"prior": "0.50",
"variants": {
"spread": "0.1287",
"permissive": "0.9309",
"conservative": "0.8022"
},
"code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
"contested": false,
"stability": "MEDIUM",
"claim_type": "QUANTITATIVE",
"config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
"probability": "0.8808",
"provisional": true,
"evidence_sum": "2.000000",
"snapshot_seq": 24920,
"prior_log_odds": "0.000000",
"support_groups": 1,
"model_dependent": false,
"review_coverage": "0.25",
"truth_evaluable": true,
"assessment_state": "SUPPORTED",
"review_checklist": {
"qualifiers_reviewed": {
"by": [],
"ok": false
},
"opposing_search_done": {
"by": [],
"ok": false
},
"independence_reviewed": {
"by": [],
"ok": false
},
"primary_source_reviewed": {
"by": [
"bede249d-4466-8c9f-a2ed-ff80af9c5458",
"e9ab9c80-d5ba-8282-9c2c-113239a50f45"
],
"ok": true
}
},
"contradict_groups": 0,
"rounding_boundary": false,
"posterior_log_odds": "2.000000",
"not_applicable_reason": null,
"independence_unreviewed": 2
}