Claim
The study created a multimodal facial atlas across embryonic weeks 6–11 using single-cell transcriptomics, chromatin accessibility, and spatial transcriptomics, and characterized 56 cell states.
a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositionsTopics
Biology · 1efd24fe Medicine · 1efd24fe
Assessment
Supported
Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:f8800b17-5a0c-8bf6-acc7-a62e5842b6df
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from nature.com was not found on the page when Galedra fetched it.
Why?
Strongest counted support: The abstract reports a weeks 6–11 multimodal atlas with three single-cell or spatial modalities and 56 characterized cell states. weight 1.800000 evidence
Suppressed as dependent: The passage directly states that the atlas covered embryonic weeks 6–11, used three modalities, and characterized 56 cell states.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.
0.8581 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 2 sources, 1 independent lineage
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| 376a0a2a support | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 1.800000 |
| 932d8478 support | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (dependent strongest only, kept 376a0a2a) |
prior 0.50 → log-odds 0.000000 + 1.800000 (the counted weights) = 1.800000 → probability 0.8581
Your view
Registered views
Nobody has registered a view yet.
Checked as part of
- “A multimodal embryonic facial atlas links cell states, regulatory elements, and peripheral-nerve signaling to human facial variation and craniofacial...” · 3 claims · 29 September 2026
Evidence for
-
From Atlas of cell types and regulatory elements underlying human facial diversity Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From Atlas of cell types and regulatory elements underlying human facial diversity Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Evidence against
None.
Qualifications
None.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| 761fb532 | 376a0a2a |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 376a0a2a, 932d8478 |
Summary
Supported. The main support is: The abstract reports a weeks 6–11 multimodal atlas with three single-cell or spatial modalities and 56 characterized cell states. f6ef46a2
1 further item repeats the same origin and is not independent evidence. 761fb532
Review checks: 1 of 4. coverage:f8800b17-5a0c-8bf6-acc7-a62e5842b6df
Contribution history
| seq | event | detail |
|---|---|---|
| 24201 | APPENDED | |
| 24202 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 24219 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 24655 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
{
"claim": "f8800b17-5a0c-8bf6-acc7-a62e5842b6df",
"links": [
{
"link": "347fb372-203a-8fe5-bb26-19fc376a0a2a",
"group": null,
"edition": "NAMED_OR_UNRELATED",
"evidence": "83cb244d-9197-8775-a433-c600f6ef46a2",
"direction": "SUPPORT",
"magnitude": "1.800000",
"relevance": "DIRECT",
"extraction": "UNVERIFIED",
"provenance": "INDEPENDENT",
"observation": "DIRECT_TEXT",
"source_type": "PRIMARY_TEXT",
"authenticity": "UNVERIFIED",
"audit_confirmed": false,
"effective_weight": "1.800000",
"interpretive_steps": 0
},
{
"kept": "347fb372-203a-8fe5-bb26-19fc376a0a2a",
"link": "7e173f14-1898-86b1-8511-1bf0932d8478",
"group": null,
"reason": "dependent_strongest_only",
"edition": "NAMED_OR_UNRELATED",
"evidence": "936101fe-47bc-8787-b685-a777761fb532",
"direction": "SUPPORT",
"magnitude": "1.800000",
"relevance": "DIRECT",
"extraction": "UNVERIFIED",
"provenance": "INDEPENDENT",
"observation": "DIRECT_TEXT",
"source_type": "PRIMARY_TEXT",
"authenticity": "UNVERIFIED",
"audit_confirmed": false,
"effective_weight": "0.000000",
"interpretive_steps": 0
}
],
"model": "ledger-default@0.3.0",
"prior": "0.50",
"variants": {
"spread": "0.1331",
"permissive": "0.9121",
"conservative": "0.7790"
},
"code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
"contested": false,
"stability": "MEDIUM",
"claim_type": "QUANTITATIVE",
"config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
"probability": "0.8581",
"provisional": true,
"evidence_sum": "1.800000",
"snapshot_seq": 25730,
"prior_log_odds": "0.000000",
"support_groups": 1,
"model_dependent": false,
"review_coverage": "0.25",
"truth_evaluable": true,
"assessment_state": "SUPPORTED",
"review_checklist": {
"qualifiers_reviewed": {
"by": [],
"ok": false
},
"opposing_search_done": {
"by": [],
"ok": false
},
"independence_reviewed": {
"by": [],
"ok": false
},
"primary_source_reviewed": {
"by": [
"347fb372-203a-8fe5-bb26-19fc376a0a2a",
"7e173f14-1898-86b1-8511-1bf0932d8478"
],
"ok": true
}
},
"contradict_groups": 0,
"rounding_boundary": false,
"posterior_log_odds": "1.800000",
"not_applicable_reason": null,
"independence_unreviewed": 2
}