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Claim

The study created a multimodal facial atlas across embryonic weeks 6–11 using single-cell transcriptomics, chromatin accessibility, and spatial transcriptomics, and characterized 56 cell states.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 24201 · qualifiers {"population":"Embryonic human facial development","time_range":"Embryonic weeks 6–11"}

a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositions

Referenced 165 times: checked 1, looked up by assistants 0, viewed 119, shared 45. A count of attention, not evidence.

Topics

Biology · 1efd24fe Medicine · 1efd24fe

Assessment

Supported

Score: 0.8581 under ledger-default@0.3.0 at snapshot 27745

2 of 4 review checks done · 1 counted · 1 by the author only

1 independent evidence lineage · review checks 1 of 4 · stability MEDIUM

Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:f8800b17-5a0c-8bf6-acc7-a62e5842b6df

Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from nature.com was not found on the page when Galedra fetched it.

Why?

Strongest counted support: The abstract reports a weeks 6–11 multimodal atlas with three single-cell or spatial modalities and 56 characterized cell states. weight 1.800000 evidence

Suppressed as dependent: The passage directly states that the atlas covered embryonic weeks 6–11, used three modalities, and characterized 56 cell states.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

Hide calculation

0.8581 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 2 sources, 1 independent lineage

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:4a83a682f6b976e18135202aa999bf538254d7bd46b8f8667f60e81bc3fb0718

Last changed at entry seq 25730; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

LinkWorkingWeightCounted as
376a0a2a support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 1.800000
932d8478 support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 0.000000 (dependent strongest only, kept 376a0a2a)

prior 0.50 → log-odds 0.000000 + 1.800000 (the counted weights) = 1.800000 → probability 0.8581

Under neighbouring settings of the same model: 0.7790 to 0.9121, a spread of 0.1331.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Sign in to register whether you agree or disagree. A view is yours alone and never changes the assessment.

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

None.

Suppressed as dependent

EvidenceGroupKept instead
761fb532376a0a2a

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedyes376a0a2a, 932d8478

Summary

Supported. The main support is: The abstract reports a weeks 6–11 multimodal atlas with three single-cell or spatial modalities and 56 characterized cell states. f6ef46a2

1 further item repeats the same origin and is not independent evidence. 761fb532

Review checks: 1 of 4. coverage:f8800b17-5a0c-8bf6-acc7-a62e5842b6df

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
24201APPENDED
24202ACCEPTAUTOMATIC_AFTER_VALIDATION
24219LINK_EVIDENCEby 1efd24fe (accepted)
24655TASK_RESULTby 1efd24fe (accepted)

Score trace

{
  "claim": "f8800b17-5a0c-8bf6-acc7-a62e5842b6df",
  "links": [
    {
      "link": "347fb372-203a-8fe5-bb26-19fc376a0a2a",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "83cb244d-9197-8775-a433-c600f6ef46a2",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "347fb372-203a-8fe5-bb26-19fc376a0a2a",
      "link": "7e173f14-1898-86b1-8511-1bf0932d8478",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "936101fe-47bc-8787-b685-a777761fb532",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1331",
    "permissive": "0.9121",
    "conservative": "0.7790"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8581",
  "provisional": true,
  "evidence_sum": "1.800000",
  "snapshot_seq": 25730,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [
        "347fb372-203a-8fe5-bb26-19fc376a0a2a",
        "7e173f14-1898-86b1-8511-1bf0932d8478"
      ],
      "ok": true
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "1.800000",
  "not_applicable_reason": null,
  "independence_unreviewed": 2
}