Evidence item

The primary atlas reports 5.6 million nuclei, 1,384 donors, and regulatory signals for 14,258 genes across multiple cell resolutions. DATASET_RESULT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 18654

Source: Single-nucleus atlas of cell-type specific genetic regulation in the human brain · locator {} · excerpt hash sha256:c503625024958c2a01a4d1b3cec0287e13bbeca6f81e53380e4776c754f96ad8

Exact excerpt

Here we present a comprehensive, single-nucleus multi-ancestry atlas of genetic regulation of gene expression in the human prefrontal cortex, comprising 5.6 million nuclei from 1,384 donors of diverse ancestries. Through multi-resolution analyses spanning eight major cell classes and 27 subclasses, we identify genetic regulation for 14,258 genes, with 981 showing cell type-specific regulatory effects at the class level and 857 at the subclass level.

Linked claims

Claim	Direction	Relevance	Steps	Counted
ddba5235	SUPPORT	DIRECT	0	yes

Audits

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