Evidence item

The atlas used 5.6 million DLPFC nuclei from 1,384 diverse-ancestry PsychAD donors passing genotype and snRNA-seq quality control. DATASET_RESULT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25466

Source: Single-nucleus atlas of cell-type specific genetic regulation in the human brain · locator {} · excerpt hash sha256:6f77a185a4a2c19ef721b31aaef50d4890f45857b6fb8272254656cad7bb12eb

In this work, we collected 5.6 million nuclei from the human dorsolateral prefrontal cortex (DLPFC) of a genetically diverse set of 1,384 donors from the full PsychAD dataset, 35.6% of whom are of non-European ancestry. A total of 1,384 donors with genotype data and snRNA-seq data passing quality control were analyzed in this study.