Claim

From December 2020 to August 2023 in Connecticut, USA, this pilot randomized 35 of 65 methadone- or buprenorphine-prenatally-exposed infants younger than 48 hours; adherence was 84%, in-hospital retention 71.4%, and 14-day post-discharge retention 28.6%, while breastfeeding and stooling were exploratory outcomes.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 25469

41 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositions

Referenced 93 times: checked 0, looked up by assistants 0, viewed 93, shared 0. A count of attention, not evidence.

Topics

Not filed under any topic yet.

Assessment

Supported

Score: 0.9955 under ledger-default@0.3.0 at snapshot 27745

3 of 4 review checks done · 1 counted · 2 by the author only

3 independent evidence lineages · review checks 1 of 4 · stability HIGH

Main unresolved issue: 3 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:38203f50-a7a6-81f7-93a5-31d636747769

Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.

Related: NARROWS outgoing: Supported

Why?

Strongest counted support: Enrollment, adherence, and retention were primary outcomes; breastfeeding and stooling were exploratory. weight 1.800000 evidence

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Supported.

Hide calculation

0.9955 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability HIGH · 3 sources, 3 independent lineages

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:26aad8bc9178154b9f07afad36686a5a40366bfdb956a8c0967198ab36621cec

Last changed at entry seq 25474; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

Link	Working	Weight	Counted as
d3b2ceb2 support	relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	1.800000
aa7093b6 support	relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	1.800000
628e5d3f support	relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	1.800000

prior 0.50 → log-odds 0.000000 + 5.400000 (the counted weights) = 5.400000 → probability 0.9955

Under neighbouring settings of the same model: 0.9777 to 0.9991, a spread of 0.0214.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Evidence for

The pilot was a Connecticut double-blind study of methadone- or buprenorphine-exposed infants younger than 48 hours.

From Randomized pilot study comparing standard vs high-calorie feeding in infants with Neonatal Opioid Withdrawal Syndrome Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The study randomized 35 of 65 infants, with 84% adherence and poor post-discharge retention.

From Randomized pilot study comparing standard vs high-calorie feeding in infants with Neonatal Opioid Withdrawal Syndrome Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Enrollment, adherence, and retention were primary outcomes; breastfeeding and stooling were exploratory.

From Randomized pilot study comparing standard vs high-calorie feeding in infants with Neonatal Opioid Withdrawal Syndrome Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Evidence against

None.

Qualifications

None.

Suppressed as dependent

None.

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

From	Relationship	To
36747769	NARROWS	3a4047e6

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	d3b2ceb2, aa7093b6, 628e5d3f

Summary

Supported. The main support is: Enrollment, adherence, and retention were primary outcomes; breastfeeding and stooling were exploratory. bd0c81a5

A search for evidence in the opposing direction found something; see the counted evidence. d609b3a9

Review checks: 1 of 4. coverage:38203f50-a7a6-81f7-93a5-31d636747769

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seq	event	detail
25469	APPENDED
25470	ACCEPT	AUTOMATIC_AFTER_VALIDATION
25473	TASK_RESULT	by 1efd24fe (accepted)

Score trace

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  "contested": false,
  "stability": "HIGH",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.9955",
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  "snapshot_seq": 25474,
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  "support_groups": 3,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
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      "ok": false
    },
    "opposing_search_done": {
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    "independence_reviewed": {
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      "ok": true
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  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "5.400000",
  "not_applicable_reason": null,
  "independence_unreviewed": 3
}