Galedra
Sign in Sign up

Claim

In the Alliance A071801 randomized phase 3 trial of 242 patients with resected large brain metastases, three-to-five-session radiosurgery improved one-year surgical-bed control and median survival versus single-session radiosurgery without significant overall adverse-event differences.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 19058

33 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluable

Referenced 105 times: checked 1, looked up by assistants 0, viewed 76, shared 28. A count of attention, not evidence.

Topics

Medicine · 1efd24fe Health · 1efd24fe

Assessment

Supported

Score: 0.9468 under ledger-default@0.3.0 at snapshot 27745

0 of 4 review checks done · 0 counted

2 independent evidence lineages · review checks 0 of 4 · stability HIGH

Main unresolved issue: 3 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:3d0f1151-a657-8336-9af5-c642c3599d58

Not yet independently audited.Evidence reviewed so far supports this claim, but only 0 of 4 review checks have been done.A quoted passage from healio.com and newswise.com was not found on the page when Galedra fetched it.

Why?

Strongest counted support: The trial report gives 242 randomized patients, 87% versus 81% one-year surgical-bed control, and 29 versus 20 months median survival. weight 1.800000 evidence

Suppressed as dependent: The passage directly reports the 242-patient trial, improved one-year surgical-bed control, and median survival difference.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed, primary source reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.

Hide calculation

0.9468 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 0 of 4 · stability HIGH · 3 sources, 2 independent lineages

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:2161c3f6bf640934475f42d744438db2b81ca3bea9972cc56b30b3617960be5f

Last changed at entry seq 19098; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

LinkWorkingWeightCounted as
6b6500c0 support relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 1.800000
6d577be2 support relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.800000 0.000000 (dependent strongest only, kept 6b6500c0)
139554c9 support relevance STRONG 1.2 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 1.080000 1.080000

prior 0.50 → log-odds 0.000000 + 2.880000 (the counted weights) = 2.880000 → probability 0.9468

Under neighbouring settings of the same model: 0.8825 to 0.9769, a spread of 0.0944.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Sign in to register whether you agree or disagree. A view is yours alone and never changes the assessment.

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

None.

Suppressed as dependent

EvidenceGroupKept instead
b71b3cf36b6500c0

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 0 of 4

1 check by this claim's own author. No independent review yet. 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedno

Summary

Supported. The main support is: The trial report gives 242 randomized patients, 87% versus 81% one-year surgical-bed control, and 29 versus 20 months median survival. e8d2c466

1 further item repeats the same origin and is not independent evidence. b71b3cf3

Review checks: 0 of 4. coverage:3d0f1151-a657-8336-9af5-c642c3599d58

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
19058APPENDED
19059ACCEPTAUTOMATIC_AFTER_VALIDATION
19066LINK_EVIDENCEby 1efd24fe (accepted)
19068LINK_EVIDENCEby 1efd24fe (accepted)
19097TASK_RESULTby 1efd24fe (accepted)

Score trace

{
  "claim": "3d0f1151-a657-8336-9af5-c642c3599d58",
  "links": [
    {
      "link": "38f0bfd5-cb88-86be-96b5-a6cc6b6500c0",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "c8b80e36-1433-863a-8899-5f0ce8d2c466",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DATASET_RESULT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "38f0bfd5-cb88-86be-96b5-a6cc6b6500c0",
      "link": "bd91af50-c68e-801a-be75-d83c6d577be2",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "edbb4908-8236-86ee-a066-bbf3b71b3cf3",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "d257ebfc-08f9-8059-963a-9c8b139554c9",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "bb16dd05-78e3-83a2-9036-4cb9e1a73569",
      "direction": "SUPPORT",
      "magnitude": "1.080000",
      "relevance": "STRONG",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.080000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.0944",
    "permissive": "0.9769",
    "conservative": "0.8825"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "HIGH",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.9468",
  "provisional": true,
  "evidence_sum": "2.880000",
  "snapshot_seq": 19098,
  "prior_log_odds": "0.000000",
  "support_groups": 2,
  "model_dependent": false,
  "review_coverage": "0.00",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [],
      "ok": false
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "2.880000",
  "not_applicable_reason": null,
  "independence_unreviewed": 3
}