Claim

The study's analysis of APN orthologues from 93 species found restricted EriCoV receptor tropism, primarily using hedgehog APN and, to a lesser extent, felid APN.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 21265 · qualifiers {"population":"APN orthologues from 93 species tested for EriCoV receptor tropism","time_range":"study published 2026","denominator":"93 species"}

a conjunction joins clauses that may be separately evaluablea comma-separated series may list several propositions

Referenced 98 times: checked 2, looked up by assistants 0, viewed 64, shared 32. A count of attention, not evidence.

Topics

Biology · 1efd24fe Public health · 1efd24fe

Assessment

Supported

Score: 0.9121 under ledger-default@0.3.0 at snapshot 27745

2 of 4 review checks done · 1 counted · 1 by the author only

2 independent evidence lineages · review checks 1 of 4 · stability MEDIUM

Main unresolved issue: 3 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:c1922c78-a96c-8370-ae55-a9b135fa37bf

Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.

Why?

Strongest counted support: The abstract directly reports restricted receptor tropism across 93 APN orthologues, with primary hedgehog and lesser felid usage. weight 1.800000 evidence

Suppressed as dependent: The abstract directly reports restricted EriCoV tropism across 93 APN orthologues, primarily hedgehog and secondarily felid APN.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

Hide calculation

0.9121 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 3 sources, 2 independent lineages

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:bcc2418c3d616e0267946ce245decbdeedcc41bc941b82fa83d6bfeea875d53d

Last changed at entry seq 25586; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

Link	Working	Weight	Counted as
c9eb0c89 support	relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	1.800000
8875ff2f support	relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	0.000000 (dependent strongest only, kept c9eb0c89)
959ae323 support	relevance MODERATE 0.6 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	0.540000	0.540000

prior 0.50 → log-odds 0.000000 + 2.340000 (the counted weights) = 2.340000 → probability 0.9121

Under neighbouring settings of the same model: 0.8373 to 0.9544, a spread of 0.1171.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

“The study's analysis of APN orthologues from 93 species found restricted EriCoV receptor tropism, primarily using hedgehog APN and, to a lesser extent, felid...” · 1 claim · 29 September 2026
“In a 2026 Nature Microbiology study, analysis of aminopeptidase N orthologues from 93 species found restricted hedgehog merbecovirus receptor tropism,...” · 1 claim · 29 September 2026

Evidence for

The abstract directly reports restricted receptor tropism across 93 APN orthologues, with primary hedgehog and lesser felid usage.

From Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The abstract directly reports restricted EriCoV tropism across 93 APN orthologues, primarily hedgehog and secondarily felid APN.

From Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses Read 2026-09-29 Relevance DIRECT Steps 0 Counted
An independent primary study also found restricted cross-species EriCoV receptor use across 30 mammalian APN orthologues, including no human APN usage.

From Aminopeptidase N is a receptor for hedgehog merbecoviruses Read 2026-09-29 Relevance MODERATE Steps 0 Counted

Independent Nature Microbiology study corroborates the claim's restricted-tropism component but uses a 30-species panel rather than the 93-species panel in the claim.

Evidence against

None.

Qualifications

None.

Suppressed as dependent

Evidence	Group	Kept instead
5c0032b8		c9eb0c89

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	c9eb0c89, 8875ff2f, 959ae323

Summary

Supported. The main support is: The abstract directly reports restricted receptor tropism across 93 APN orthologues, with primary hedgehog and lesser felid usage. 851e472e

1 further item repeats the same origin and is not independent evidence. 5c0032b8

Review checks: 1 of 4. coverage:c1922c78-a96c-8370-ae55-a9b135fa37bf

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seq	event	detail
21265	APPENDED
21266	ACCEPT	AUTOMATIC_AFTER_VALIDATION
21271	LINK_EVIDENCE	by 1efd24fe (accepted)
21273	TASK_RESULT	by 1efd24fe (accepted)
21281	LINK_EVIDENCE	by 1efd24fe (accepted)

Score trace

{
  "claim": "c1922c78-a96c-8370-ae55-a9b135fa37bf",
  "links": [
    {
      "link": "2df324d0-f141-820d-9a52-0fa9c9eb0c89",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "8e4f417f-76f3-82fd-97af-0b8b851e472e",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "2df324d0-f141-820d-9a52-0fa9c9eb0c89",
      "link": "79d37b16-0384-8da6-852c-ddc28875ff2f",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "1aefdee5-464f-813a-bf66-a2435c0032b8",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "821b2a44-5a00-8df7-a918-cd31959ae323",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "d1de3bc2-980b-8b70-8b8a-c74670765659",
      "direction": "SUPPORT",
      "magnitude": "0.540000",
      "relevance": "MODERATE",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.540000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1171",
    "permissive": "0.9544",
    "conservative": "0.8373"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.9121",
  "provisional": true,
  "evidence_sum": "2.340000",
  "snapshot_seq": 25586,
  "prior_log_odds": "0.000000",
  "support_groups": 2,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [
        "2df324d0-f141-820d-9a52-0fa9c9eb0c89",
        "79d37b16-0384-8da6-852c-ddc28875ff2f",
        "821b2a44-5a00-8df7-a918-cd31959ae323"
      ],
      "ok": true
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "2.340000",
  "not_applicable_reason": null,
  "independence_unreviewed": 3
}