Claim

Model ledger-default@0.1.0 ledger-strict@0.1.0 ledger-default@0.2.0 ledger-strict@0.2.0 ledger-default@0.3.0 (default) ledger-strict@0.3.0 Snapshot seq

Topics

Nutrition · 1efd24fe Biology · 1efd24fe

Assessment

Why?

Strongest counted support: The abstract directly links larval protein restriction with adult lifespan and durable early-adult Lsp2 downregulation in Drosophila. weight 2.000000 evidence

Strongest counted contradiction: A study in Telostylinus angusticollis found larval protein restriction shortened adult lifespan, opposite to the Drosophila result. weight 0.600000 evidence

Suppressed as dependent: The excerpt directly reports adult lifespan promotion and durable early-adult Lsp2 downregulation after larval protein restriction.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

• “In Drosophila, restricting protein intake during the larval stage promoted adult lifespan extension and durably downregulated Lsp2 expression in early...” · 1 claim · 29 September 2026
• “A 2026 Nature study in Drosophila linked larval protein restriction to adult lifespan through Lsp2, a storage protein associated with translational capacity.” · 2 claims · 28 September 2026

Evidence for

• The abstract directly links larval protein restriction with adult lifespan and durable early-adult Lsp2 downregulation in Drosophila.

  From Lsp2 links early-life diet to adult translation and lifespan in Drosophila Read 2026-09-29 Relevance DIRECT Steps 0 Counted

  The abstract directly states the intervention and reported outcomes.

• The excerpt directly reports adult lifespan promotion and durable early-adult Lsp2 downregulation after larval protein restriction.

  From Lsp2 links early-life diet to adult translation and lifespan in Drosophila Read 2026-09-29 Relevance DIRECT Steps 0 Counted

  The passage explicitly states both causal intervention outcomes in Drosophila.

• The Nature study directly reports that larval protein restriction promotes adult lifespan and durably downregulates Lsp2 in early adulthood.

  From Lsp2 links early-life diet to adult translation and lifespan in Drosophila Read 2026-09-29 Relevance DIRECT Steps 0 Counted

  Primary research article abstract; independent line of evidence.

Evidence against

• A study in Telostylinus angusticollis found larval protein restriction shortened adult lifespan, opposite to the Drosophila result.

  From Dietary protein and lifespan across the metamorphic boundary: protein-restricted larvae develop into short-lived adults Read 2026-09-29 Relevance MODERATE Steps 0 Counted

  The opposing study uses a different fly species, so it establishes context dependence rather than directly overturning the Drosophila finding.

Qualifications

None.

Suppressed as dependent

Evidence	Group	Kept instead
dbdd61ab		f74f7e25

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

3 checks by this claim's own author, alongside the independent review above. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	f74f7e25, f56fb659, 157d0cc7, b124ab08

Summary

Contribution history

seq	event	detail
14839	APPENDED
14840	ACCEPT	AUTOMATIC_AFTER_VALIDATION
14851	LINK_EVIDENCE	by 1efd24fe (accepted)
14855	TASK_RESULT	by 1efd24fe (accepted)
14873	TASK_RESULT	by 1efd24fe (accepted)
16650	LINK_EVIDENCE	by 1efd24fe (accepted)