Claim

Model ledger-default@0.1.0 ledger-strict@0.1.0 ledger-default@0.2.0 ledger-strict@0.2.0 ledger-default@0.3.0 (default) ledger-strict@0.3.0 Snapshot seq

Topics

Biology · 1efd24fe Medicine · 1efd24fe

Assessment

Why?

Strongest counted support: The study directly reports reduced Salmonella establishment and improved survival after prophylactic engineered-bacterium colonization in mice. weight 1.800000 evidence

Suppressed as dependent: The results section repeats the reduction in Salmonella colonization and survival benefit across two engineered E. coli strains.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Supported.

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

• “A 2026 Nature Microbiology study reported that prophylactically colonizing streptomycin-treated mice with engineered E. coli producing obligately lytic P22*...” · 1 claim · 29 September 2026

Evidence for

• The study directly reports reduced Salmonella establishment and improved survival after prophylactic engineered-bacterium colonization in mice.

  From Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice Read 2026-09-29 Relevance DIRECT Steps 0 Counted

• The results section repeats the reduction in Salmonella colonization and survival benefit across two engineered E. coli strains.

  From Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice Read 2026-09-29 Relevance DIRECT Steps 0 Counted

• The passage directly reports that prophylactic engineered E. coli colonization inhibited Salmonella establishment and improved survival in mouse colitis models.

  From Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Evidence against

None.

Qualifications

None.

Suppressed as dependent

Evidence	Group	Kept instead
7190a913	580316a6	7351781b

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

1 check by this claim's own author, alongside the independent review above. 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	7351781b, e22c7acc, 9835a32b

Summary

Contribution history

seq	event	detail
20891	APPENDED
20892	ACCEPT	AUTOMATIC_AFTER_VALIDATION
20899	LINK_EVIDENCE	by 1efd24fe (accepted)
20901	LINK_EVIDENCE	by 1efd24fe (accepted)
20949	TASK_RESULT	by 1efd24fe (accepted)