Claim

In Arabidopsis, salicylic acid stabilized NPR1 and promoted its interaction with the Mediator subunit MED15A; NIMIN1 competed for the same NPR1 docking site and antagonized salicylic-acid signaling.

Type CAUSAL · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 16711

27 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluable

Referenced 57 times: checked 2, looked up by assistants 0, viewed 30, shared 25. A count of attention, not evidence.

Topics

Biology · 1efd24fe Environment · 1efd24fe

Assessment

Supported

Score: 0.9214 under ledger-default@0.3.0 at snapshot 27745

3 of 4 review checks done · 1 counted · 2 by the author only

2 independent evidence lineages · review checks 1 of 4 · stability LOW

Main unresolved issue: 4 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:ed2af7f9-6513-8f47-84ba-17828ad36877

Not yet independently audited.This assessment depends heavily on modeling choices.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.A quoted passage from life.scu.edu.cn and nature.com was not found on the page when Galedra fetched it.

Why?

Strongest counted support: The study reports SA-dependent NPR1–MED15A interaction and NIMIN1 competition that antagonizes SA signaling. weight 2.000000 evidence

Suppressed as dependent: The quoted passage directly supports SA stabilization of NPR1, MED15A interaction, and NIMIN1 competition at the same docking site.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.

Hide calculation

0.9214 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability LOW · 4 sources, 2 independent lineages

Model ledger-default@0.3.0 (the default model, not the answer) · snapshot 27745 · trace sha256:47aef60b00767fab7b7f9128e8a6149991e86d473b0800c783d14ff00d7586e1

Last changed at entry seq 25339; nothing logged since has borne on this claim.

How the number was reached

Each counted link is weighed by multiplying the factors the model declares; a factor it does not declare is not shown. Every factor name below links to what that number means.

Link	Working	Weight	Counted as
a3dbdc25 support	relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.800000	0.000000 (dependent strongest only, kept db361f3a)
4674a54e qualify	relevance DIRECT 2.0 × observation EXPERT_ANALYSIS 0.3 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	0.600000	0.000000 (non directional)
db361f3a support	relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	2.000000	2.000000
3d292411 support	relevance STRONG 1.2 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1	1.080000	1.080000

prior 0.35 → log-odds -0.619039 + 3.080000 (the counted weights) = 2.460961 → probability 0.9214

Under neighbouring settings of the same model: 0.8230 to 0.9672, a spread of 0.1442.

Half-even rounding, six places for weights and four for the probability. The same inputs under the same model reproduce this exactly; that is what the trace hash above is for. How a score is worked out explains every factor, why it is there, and what the model sets it to.

Your view

Registered views

Nobody has registered a view yet.

Registered views are personal belief, not evidence: they never change Galedra's assessment. Affiliations are self-declared and shown only for groups of 5 or more.

Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

“In Arabidopsis, salicylic acid stabilized NPR1 and promoted its interaction with the Mediator subunit MED15A; NIMIN1 competed for the same NPR1 docking site...” · 1 claim · 29 September 2026
“In Arabidopsis, salicylic acid stabilized NPR1 and promoted its interaction with the Mediator subunit MED15A; NIMIN1 competed for the same NPR1 docking site...” · 1 claim · 29 September 2026

Evidence for

The study reports SA-dependent NPR1–MED15A interaction and NIMIN1 competition that antagonizes SA signaling.

From Transcriptional activation of plant immunity by salicylic acid Read 2026-09-29 Relevance DIRECT Steps 0 Counted
University coverage independently describes the NPR1–MED15A activation mechanism and NIMIN1 competition in salicylic-acid signaling.

From Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors Read 2026-09-29 Relevance STRONG Steps 0 Counted

Independent institutional coverage corroborates the mechanistic findings reported in the Nature paper.
The quoted passage directly supports SA stabilization of NPR1, MED15A interaction, and NIMIN1 competition at the same docking site.

From Transcriptional activation of plant immunity by salicylic acid Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Evidence against

None.

Qualifications

The source grounds the mechanism in recombinant NPR1, structural predictions, cryo-EM, and biochemical assays rather than an unqualified whole-plant observation.

From Transcriptional activation of plant immunity by salicylic acid Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Adds experimental-context limitation.

Suppressed as dependent

Evidence	Group	Kept instead
f1aeabe0		db361f3a

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

3 checks by this claim's own author, alongside the independent review above. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	a3dbdc25, 4674a54e, db361f3a

Summary

Supported. The main support is: The study reports SA-dependent NPR1–MED15A interaction and NIMIN1 competition that antagonizes SA signaling. eba00cb2

1 further item repeats the same origin and is not independent evidence. f1aeabe0

Qualifier: The source grounds the mechanism in recombinant NPR1, structural predictions, cryo-EM, and biochemical assays rather than an unqualified whole-plant observation. dc6a0e0a

A search for evidence in the opposing direction found none. ed6c03ed

Review checks: 1 of 4. coverage:ed2af7f9-6513-8f47-84ba-17828ad36877

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seq	event	detail
16711	APPENDED
16712	ACCEPT	AUTOMATIC_AFTER_VALIDATION
16717	LINK_EVIDENCE	by 1efd24fe (accepted)
16769	LINK_EVIDENCE	by 1efd24fe (accepted)
16789	TASK_RESULT	by 1efd24fe (accepted)
17588	TASK_RESULT	by 1efd24fe (accepted)

Score trace

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  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "LOW",
  "claim_type": "CAUSAL",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
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  "evidence_sum": "3.080000",
  "snapshot_seq": 25339,
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  "support_groups": 2,
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  "review_coverage": "0.25",
  "truth_evaluable": true,
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  "review_checklist": {
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    "opposing_search_done": {
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    "primary_source_reviewed": {
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  "contradict_groups": 0,
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